Jared, thanks. Yes I've been talking to Sam about it and I have tried two previous ASCOM driver versions which did have memory issues as mentioned. This is definitely different. There is no hub involved. The camera is connected directly to the USB 3.0 port on my laptop with the USB 3.0 cable provided with the camera. When I did previous runs I could do thousands of images over many hours with no problems as you say. This just started happening yesterday afternoon. It is possible that my previous testing was with a different cable. I have several lying around and might have used a different one previously since the one from the camera is pretty short. I can try with a different cable tonight if you think it might be related to that. I can also test connected to a powered hub rather than directly to the laptop, but my previous testing was direct to the laptop as well.
I'm still waiting for some filter wheel adapters to do the final mounting of my imaging train on my scope and connect it to my normal hub setup, so that's really the configuration I should be testing. I may attach it through that setup to test also even without the correct mechanical adapters to mount the camera.