On topic : On Win10, the following is working fine
SGP v 2.5.1.14
PlateSolve 2, Elbrus, or ANSVR local install. All seem fine.
Gemini.NET 1.0.62 ASCOM driver
Atik 314L+ w/ standard ASCOM drivers
PHD2 2.6.1
QHY5L II w/ standard ASCOM drivers
So there's that.
Off topic :
I abhor the "modern" interface...it's bubblegum crap for "the mobile world". The good news is, it's really not hard to get Win 10 into a very Win7-esque look, with standard settings and no 3rd party addons. You can remove "app tiles", hide "Cortana", and change to a "Classic" start menu all with just a few right clicks in the right places.
Once that's done, if you're so inclined, you can do a bit deeper digging for things like configuring network interfaces as "metered" to stop forced auto updates, or regedit the lock screen away.
I've got 3 Win10 machines now, including my main processing PC. 1 was a native install (new laptop) the other both upgrades, and all are fine.
Further off-topic
If you haven't actually spent some time with it, give it a shot if you can. It's really a pretty dang nice OS once you realize you can navigate in a manner that's comfortable for you.